SEDANZA PDRN Ampoule with cosmetic syringe
Visible radiance from the first application
Why it works: PDRN micro-mesh, glow and syringe application
Fine lines less visible
Key ingredients: PDRN and Vitamin B12
Smile lines softened
Perfect dose: 0.5 ML in the morning, 1 ML at night
Crow's feet reduced
Dermatologist tested
PDRN Ampoule compared with a regular face cream
Visibly more rested face
More even, less dull skin tone
99-day guarantee: guaranteed results or a full refund
SEDANZA PDRN Ampoule with cosmetic syringe
Visible radiance from the first application
Why it works: PDRN micro-mesh, glow and syringe application
Fine lines less visible
Key ingredients: PDRN and Vitamin B12
Smile lines softened
Perfect dose: 0.5 ML in the morning, 1 ML at night
Crow's feet reduced
Dermatologist tested
PDRN Ampoule compared with a regular face cream
Visibly more rested face
More even, less dull skin tone
99-day guarantee: guaranteed results or a full refund

New from Sedanza
4.8

SEDANZA – PDRN Ampoule for Instant Radiance

Brighter, fresher, more vibrant skin from the very first application. Salmon DNA (PDRN) and Vitamin B12 revitalize dull cells and give your face back the glow that stress and fatigue had taken away. Results Guaranteed or Your Money Back.

Instant Radiance Effect
Revitalized, Even-Toned Face
Korean Technology 2026
Professional Treatment
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PRODUCT DESCRIPTION

An ampoule made for women who want a radiant, even complexion... not months from now, but from the very first application.

Your skin has an invisible shield, the stratum corneum, that blocks almost everything you put on it. Radiance fades and marks form deep down, where the collagen-producing cells live. Traditional creams never reach that far.

Retinol regenerates, but it can irritate. Hyaluronic acid hydrates, but it stays on the surface. Invasive treatments are expensive and harsh. None of these solutions brings back radiance and support where they're needed.

PDRN is small enough to get through that shield. Once inside, it supports skin renewal and helps restore radiance and an even tone.

Vitamin B12, the "Pink Vitamin", revives dull skin and gives it a visible glow.

The multi-peptide complex (Copper Tripeptide-1 and others) supports firmness and elasticity, backing up that radiance.

Collagen and 8 types of Hyaluronic Acid hydrate the skin on multiple levels, keeping it plump and more evenly luminous.

The result is immediate and progressive: skin looks brighter, fresher and more even from the first use, and your tone improves week after week.

The needle-free cosmetic syringe lets you dose precisely and apply the ampoule only where you need it: eye contour, expression lines, smile lines. Like a professional treatment, done at home.

HOW DO I USE IT?

Use the ampoule 2 times a day, morning and night, on clean skin, after toner and before your moisturizer.

1. Draw your dose with the needle-free cosmetic syringe: 0.5 ml in the morning · 1 ml at night.

2. Apply to the areas you want to treat (eye contour, expression lines, smile lines) and massage in circular motions until the pink filaments dissolve into the skin.

3. Repeat every day. With consistency, skin looks brighter, firmer and more elastic week after week.

The texture is lightweight, non-sticky and works great under makeup too.

PROVEN INGREDIENTS

PDRN — DNA fragments small enough to get past the surface barrier. Supports the skin's natural renewal and creates a network that leaves it plumper, more elastic and more radiant from within.

Vitamin B12 (Pink Vitamin) — The glow engine: revives dull, tired-looking skin, and gives the ampoule its signature pink color.

Niacinamide — Vitamin B3, one of the most studied actives in cosmetics. Evens out skin tone, reduces redness and dark spots, and strengthens the skin barrier.

Soluble Collagen — Retains water and keeps skin soft and firm. With consistent use, it helps counter that hollow, deflated look.

Multi Hyaluronic Acid — Eight different forms: from those that stay on the surface for an instant plumping effect, to low-weight ones that work deeper. Multi-level hydration that lasts.

Multi-peptide complex — Copper Tripeptide-1, Acetyl Hexapeptide-8, Palmitoyl Pentapeptide-4 and other peptides that support firmness and elasticity.

For the full INCI list, see the FAQ at the bottom of the page.

99-DAY SATISFACTION OR MONEY-BACK GUARANTEE

We know that choosing a new skincare product takes trust. That's why we want you to try the SEDANZA PDRN Ampoule completely risk-free.

Our promise is simple: if after 99 days of consistent use you're not completely satisfied with your results, we'll refund you in full. No questions asked, no hassle.

SHIPPING & CONTACT

Your order ships within 24-48 hours of purchase.

Free shipping, with delivery in 7-9 business days.

Within 24 hours, you'll receive your tracking code by email.

Our customer service team is here to help at soporte@sedanza.com

Excellent
The glow effect our customers love SEDANZA

MORE RADIANT FACE

Sofía R.

Verified Customer

I used to wake up with dull, grayish skin. Since I started using the ampoule, my face looks so much brighter and fresher, like I actually got a good night's sleep. I'm never giving it up!

MORE EVEN TONE

Alejandra P.

Verified Customer

My skin tone was uneven, with dull patches. Within a few weeks my face looks so much more even and my skin catches the light. I don't skip a single day. Even my makeup looks better!

FRESHER-LOOKING EYES

Daniela L.

Verified Customer

My under-eyes always looked tired and dull. Now my eye area looks brighter and more rested, and my eyes look more open. I put it on in the morning and I'm good to go. It saves me when I barely sleep.

THE SECRET TO A FACE THAT GLOWS

Vitamin B12, the "Pink Vitamin," revives dull skin and gives it a visible glow from the very first application.

PDRN and Niacinamide even out skin tone and support skin renewal, for a fresher, more radiant face over time.

Hyaluronic Acid hydrates and plumps: plump, smooth skin reflects light better, so your tone looks more radiant.

  • icon
    Visible radiance from the very first moment
  • Hydrates and keeps skin plump
  • A more even, fresher-looking face

YOUR JOURNEY, DAY BY DAY

For maximum results, apply the ampoule twice a day, morning and night.

DAY 1
Apply the ampoule with the syringe and watch the pink PDRN filaments melt into your skin.
Take a "before" photo: it will be your point of comparison.
PDRN and Vitamin B12 start brightening your skin from the very first use.
DAY 2
In the morning, your skin looks brighter and fresher, with a more even tone.
Overnight, the Pink Vitamin revived your dull skin.
Your nighttime ritual becomes your favorite moment of the day.
DAY 10
Compare today's photo with the one from day one.
Your face looks more even and dull areas look revived.
Someone starts noticing how healthy your skin looks.
DAY 30
Your side-by-side photos tell the whole story.
Your skin has a natural, fresh, even glow, like you just got back from vacation.
And when people ask for your secret, you'll know exactly what to say.

Every ingredient has a precise role

Suitable for Sensitive Skin Suitable for Sensitive Skin
Cruelty Free Cruelty Free
Visible Glow Effect Visible Glow Effect
Fragrance-Free Fragrance-Free
Suitable for Sensitive Skin Suitable for Sensitive Skin
Cruelty Free Cruelty Free
Visible Glow Effect Visible Glow Effect
Fragrance-Free Fragrance-Free
Suitable for Sensitive Skin Suitable for Sensitive Skin
Cruelty Free Cruelty Free
Visible Glow Effect Visible Glow Effect
Fragrance-Free Fragrance-Free
Suitable for Sensitive Skin Suitable for Sensitive Skin
Cruelty Free Cruelty Free
Visible Glow Effect Visible Glow Effect
Fragrance-Free Fragrance-Free

Formulated by Experts
Dermatologist Approved

The SEDANZA PDRN Ampoule puts the spotlight on Vitamin B12, the "Pink Vitamin," together with PDRN and Niacinamide to revive dull skin and give it a visible glow. One simple step for a fresher, brighter, more even tone, day after day.

SEDANZA Dermatologist
99-day satisfaction guarantee
99-day satisfaction guarantee

3 simple steps for an at-home treatment

Step 1
1

Draw up your dose with the cosmetic syringe.
0.5 ml in the morning · 1 ml at night

Step 2
2

Massage in with circular motions.
PDRN and the pink filaments brighten and revive your skin

Step 3
3

Repeat every day. With consistency, your skin looks brighter, firmer and more elastic week after week.

Frequently Asked Questions

Collapsible content

Ingredients are listed using INCI nomenclature, the international standard for all cosmetics:

✔ Vitamin B12 (Pink Vitamin) + PDRN + Niacinamide: the actives that brighten your face

Aqua, Butylene Glycol, Glycerin, Niacinamide, Caprylhydroxamic Acid, Propylene Glycol, Glyceryl Caprylate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Arginine, Methylparaben, Adenosine, Carbomer, Hydrolyzed DNA, Disodium EDTA, Cyanocobalamin, CI 77891, Calcium Alginate, Gellan Gum, Agar, Phenoxyethanol, 1,2-Hexanediol, Caprylyl Glycol, CI 12490, Copper Tripeptide-1, Pentylene Glycol, PPG-13-Decyltetradeceth-24, Carnosine, Oligopeptide-1, Acetyl Hexapeptide-8, Palmitoyl Pentapeptide-4, Hexapeptide-9, Acetyl Tetrapeptide-3, Acetyl Tetrapeptide-9, Acetyl Tetrapeptide-11, Nonapeptide-1, Palmitoyl Tripeptide-8, Collagen Extract, Collagen, Soluble Collagen, Elastin, Fibronectin, Xanthan Gum, Glucose, Sodium Hyaluronate, Chondrus Crispus Extract, Hydroxypropyltrimonium Hyaluronate, Hydrolyzed Hyaluronic Acid, Sodium Acetylated Hyaluronate, Hyaluronic Acid, Sodium Hyaluronate Crosspolymer, Hydrolyzed Sodium Hyaluronate, Potassium Hyaluronate.

Formula

❌ Paraben-free
❌ Mineral oil-free
❌ Phthalate-free
❌ No harsh ingredients
🐰 Cruelty Free

PDRN is an active made of DNA fragments so small they get past the surface barrier and work at a deeper cosmetic level, where lines begin to form.

There, it supports the skin's natural renewal and builds a network that leaves it plumper, more elastic and more radiant from within.

They're PDRN microfilaments suspended in the serum, along with the natural agents that give them structure (alginate, gellan gum and agar).

As you massage, they melt into your skin and release the actives gradually.

The pink color comes from Vitamin B12, the "Pink Vitamin," and from the cosmetic pigments in the formula.

They're a signature of the ampoule, not a defect: it's normal to see them settle at the bottom.

The cosmetic syringe is needle-free: it doesn't sting and it doesn't hurt. Draw up 0.5 ml in the morning and 1 ml at night and apply it directly to wrinkles, the eye area and smile lines.

The glow and radiance are often visible from the very first application; skin tone evenness and freshness improve progressively with consistent use. We recommend a cycle of at least 99 days.

Yes. It's designed for daily use and is also suitable for sensitive skin. Apply it to clean skin, after toner and before moisturizer; the texture is lightweight, non-sticky and works great under makeup too.

You can try it risk-free.

If you're not satisfied with the results, you have 99 days to request a full refund: love it or your money back.

Fewer than 1% of customers have asked for a refund.

Your glow, by the numbers

0%

noticed a visibly more radiant face from the first few applications.

0%

saw a more even, less dull skin tone.

0%

would recommend the ampoule for its glow effect.

Study conducted with 1,000 customers aged 40 to 50 after 30 days.

Our customers' reviews

4.8

Reviews from our store in Italy, translated into English

  • Valentina G. · Italy Verified Purchase
    August 2026
    Radiant, silky skin!

    I didn't expect it, truly excellent. I'll definitely buy it again!

  • Fabiana C. · Italy Verified Purchase
    August 2026
    More radiant and hydrated

    My skin went from dull to so much more radiant and so much more hydrated!

  • Silvia R. · Italy Verified Purchase
    More radiant face

    My skin tends to look dull and grayish in the mornings. Since I started using the ampoule, my face looks visibly brighter and fresher: it's like I slept better. It's my new must-have.

Email: soporte@sedanza.com

Availability: Mon-Sat, 9 AM to 6 PM

99-Day Guarantee

Try it risk-free. Get results or a full refund

Dermatologically Tested

Tested to ensure safety and skin compatibility.

Free Shipping

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Dedicated Customer Service

Our team is always available to help you with anything you need.